Protein crystallization

Revolutionize your protein crystallography experiments with automation to enhance reproducibility and cost-effectiveness.

Time-consuming and expensive experiments become streamlined, ensuring stable and comparable results through automated processes. Our technology handles low-volumes adeptly, minimizing the consumption of valuable materials. Elevate the efficiency of your experiments, making protein crystallography more accessible and resource-efficient.

Save expensive reagent

Optimize your resources with our advanced technology – aspirate minimal sample quantities from a source plate using PIPEJET®. The dead volume in PIPEJET® pipes is mere µl, ensuring efficient transfer to the protein crystallography plate. Maximize your experimental efficiency while conserving valuable stock materials with our precision-driven solutions.

Sitting drop

Optimization for your website: Elevate your protein crystallography experiments with precision, dispensing single droplets in the precise range of 2 - 70 nanoliters onto crystallography plates.

  • Cost Efficiency: Transfer small nanoliter volumes to significantly reduce reagent costs.
  • Enhanced Productivity: Increase the number of crystallization runs with the optimized dispensing system.
  • Contamination Prevention: Minimize the risk of contamination with precise, controlled droplet deposition.
  • Reproducibility: Achieve reproducible and comparable experimental results, ensuring the reliability of your research.

Choose our technology for a more efficient and cost-effective protein crystallography workflow.

Relevant literature

On-demand droplet loading of ultrasonic acoustic levitator and its application for protein crystallography experiments | 2019

In this Letter, we explore a method of loading small droplets by using DoD dispensers to eject droplets and capturing those by the acoustic levitator. By analyzing the required condition for the trapping, we have developed a stable trapping strategy and applied the method to conduct a pilot protein crystallography experiment. In this way, we showed that the combination of the DoD dispensing method with the ALD is promising to realize an automated X-ray diffraction experiment without solid containers for crystals.

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Automated harvesting and processing of protein crystals through laser photoablation

Currently, macromolecular crystallography projects often require the use of highly automated facilities for crystallization and X-ray data collection. However, crystal harvesting and processing largely depend on manual operations. Here, a series of new methods are presented based on the use of a low X-ray-background film as a crystallization support and a photoablation laser that enable the automation of major operations required for the preparation of crystals for X-ray diffraction experiments.

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